Folate-PEG1 DBCO Amide is a bioconjugation compound engineered for precise, receptor-specific drug delivery. It combines a folate group that targets cancer cells, a PEG1 linker for improved solubility, and a DBCO group for efficient, copper-free click chemistry with azides, making it ideal for cancer-targeting applications.
Key Features:
- Folate Targeting: Targets folate receptors often overexpressed in cancer cells, allowing for selective and efficient drug delivery.
- PEG Spacer: The PEG1 linker boosts solubility and compatibility, improving the compound’s pharmacokinetics.
- DBCO Functionality: Enables copper-free click chemistry with azides, allowing for effective and bioorthogonal conjugation.
Applications:
- Targeted Drug Delivery: Optimized for creating drug conjugates aimed at cancer cells with high folate receptor expression, minimizing off-target effects.
- Bioconjugation: Suitable for conjugating therapeutic agents, imaging probes, and biomolecules, enhancing targeting precision and efficacy.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.