Fmoc-NH-PEG23-acid
This product is a heterobifunctional PEG reagent with an Fmoc-protected amine on one end and a carboxylic acid on the other. The PEG23 spacer provides excellent solubility, flexibility, and long spacing, making it especially effective for orthogonal synthesis, bioconjugation, and drug delivery applications.
Key Features and Benefits:
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Fmoc-Protected Amine: Base-labile protection supports orthogonal synthesis strategies.
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Carboxylic Acid: Couples efficiently with amines for stable amide formation.
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PEG23 Spacer: Offers extended hydrophilicity, flexibility, and steric spacing.
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Orthogonal Design: Enables stepwise multi-functional conjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Links biomolecules with orthogonal PEG-based chemistry.
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Drug Delivery: Provides long-chain PEGylation to enhance solubility and circulation.
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Peptide Chemistry: Serves as a spacer or intermediate in protected syntheses.
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Material Science: Functionalizes polymers, nanoparticles, and biomaterials.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain stability.
This product combines Fmoc protection with a long PEG spacer and terminal carboxyl group, making it an especially versatile reagent for advanced conjugation, drug delivery, and material science applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
