DSPE-PEG5-propargyl
This product is a lipid–PEG conjugate containing a DSPE hydrophobic tail, a PEG5 spacer, and a terminal propargyl group. It enables liposome functionalization and copper-catalyzed click chemistry with azides, specifically providing solubility and dual reactivity.
Key Features and Benefits
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DSPE Lipid Tail: Anchors strongly into liposomes, micelles, or lipid bilayers.
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Propargyl Group: Reacts with azides via CuAAC click chemistry.
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PEG5 Spacer: Enhances solubility and provides short, flexible spacing.
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Dual Functionality: Combines lipid anchoring with click chemistry.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
Applications
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Liposome Functionalization: Introduces click handles into lipid bilayers.
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Drug Delivery: Builds PEGylated liposomal carriers with reactive groups.
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Probe Development: Creates multifunctional lipid–PEG probes for imaging.
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Material Science: Functionalizes nanoparticles and vesicles with propargyl groups.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Dissolve in chloroform, ethanol, or aqueous buffers with detergents; avoid prolonged air or moisture exposure.
This product integrates lipid anchoring with alkyne click chemistry in a PEG5 scaffold, specifically providing versatile functionality for liposomes, probes, and delivery systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
