DSG-PEG, MW 550 is an amphiphilic lipid-PEG conjugate containing a hydrophobic distearoyl glycerol (DSG) anchor and hydrophilic PEG segment with MW 550, while its relatively short PEG chain provides a compact hydrophilic spacer for lipid assembly, PEGylation, nanoparticle formulation, and biomaterial research.
Key Features and Benefits
- Amphiphilic Structure: DSG-PEG combines a hydrophobic DSG lipid anchor with a hydrophilic PEG chain.
- PEG MW 550: The MW 550 PEG segment provides hydrophilic character while maintaining a relatively compact molecular architecture.
- DSG Lipid Anchor: The distearoyl glycerol group specifically provides a hydrophobic anchor for incorporation into lipid-based assemblies.
- Compact PEG Spacer: The shorter PEG chain offers reduced spacer length compared with higher molecular weight DSG-PEG variants.
- PEGylated Lipid Platform: The PEG segment introduces hydrophilic character to DSG-containing lipid systems.
- Lipid Assembly Capability: The amphiphilic architecture specifically supports incorporation into liposomes, lipid nanoparticles, and related lipid systems.
- Surface Modification: DSG anchoring can introduce short PEG chains onto compatible lipid and hydrophobic surfaces.
- Biomaterial Platform: DSG-PEG provides a versatile building block for lipid-based and PEG-containing material systems.
Applications
- Lipid Nanoparticle Research: Researchers use DSG-PEG, MW 550 to investigate PEG-containing lipid nanoparticle formulations.
- Liposome Research: Supports incorporation of short PEG segments into liposomal and related lipid assemblies.
- PEGylation Research: Provides a compact lipid-anchored PEG component for studying PEG-modified lipid systems.
- Nanoparticle Formulation: Supports development and evaluation of lipid-based nanoparticles and nanoscale formulations.
- Lipid Assembly Research: Enables investigation of amphiphilic lipid-PEG organization and material properties.
- Surface Modification: Supports PEG modification of compatible lipid and hydrophobic surfaces.
- Drug Delivery Research: Provides an amphiphilic lipid-PEG component for experimental delivery-system development.
- Biomaterial Research: Supports development of functional lipid-PEG materials and nanoscale biomaterial systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
DSG-PEG, MW 550 combines a hydrophobic DSG lipid anchor with a compact hydrophilic PEG segment and specifically supports lipid nanoparticles, liposomes, PEGylation, surface modification, drug delivery, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
