DSG-PEG, MW 2K is an amphiphilic lipid-PEG conjugate containing a hydrophobic distearoyl glycerol (DSG) anchor and hydrophilic 2K PEG segment that specifically supports lipid assembly, PEGylation, nanoparticle formulation, liposome research, and biomaterial development.
Key Features and Benefits
- Amphiphilic Structure: DSG-PEG combines a hydrophobic DSG lipid anchor with a hydrophilic PEG chain.
- PEG MW 2K: The 2K PEG segment provides hydrophilic character and supports interactions with aqueous environments.
- DSG Lipid Anchor: The distearoyl glycerol group provides a hydrophobic anchor for incorporation into lipid-based assemblies.
- PEGylated Lipid Platform: The PEG chain provides a hydrophilic polymer segment attached to the DSG lipid anchor.
- Lipid Assembly Capability: The amphiphilic architecture specifically supports incorporation into liposomes, lipid nanoparticles, and related lipid systems.
- Surface Modification: DSG anchoring can introduce PEG chains onto compatible lipid and hydrophobic surfaces.
- Formulation Versatility: The combination of lipid and PEG segments specifically supports research across diverse nanoscale formulations.
- Biomaterial Platform: DSG-PEG specifically provides a useful building block for lipid-based and PEG-containing material systems.
Applications
- Lipid Nanoparticle Research: Researchers use DSG-PEG, MW 2K in the development and evaluation of PEG-containing lipid nanoparticles.
- Liposome Research: Supports incorporation of PEG segments into liposomal and related lipid assemblies.
- PEGylation Research: Provides a lipid-anchored PEG component for studying PEG-modified lipid systems.
- Nanoparticle Formulation: Supports development of lipid-based nanoparticles and other nanoscale formulations.
- Lipid Assembly Research: Enables investigation of amphiphilic lipid-PEG organization and material properties.
- Surface Modification: Supports PEG modification of compatible lipid and hydrophobic surfaces.
- Drug Delivery Research: Provides an amphiphilic lipid-PEG component for experimental delivery-system development.
- Biomaterial Research: Supports development of functional lipid-PEG materials and nanoscale biomaterial systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
DSG-PEG, MW 2K combines a hydrophobic DSG lipid anchor with a hydrophilic PEG segment in an amphiphilic structure and specifically supports lipid nanoparticles, liposomes, PEGylation, surface modification, drug delivery, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.

