DNP-PEG4-t-butyl ester
This product is a heterobifunctional linker featuring a dinitrophenyl (DNP) hapten for antibody recognition and a t-butyl ester as an acid-labile protecting group. The PEG4 spacer provides solubility and flexibility, making it especially useful in immunology research, probe development, and multifunctional conjugation.
Key Features and Benefits:
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DNP Moiety: Enables strong antibody recognition in immunology applications.
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t-Butyl Ester: Provides acid-labile protection for stepwise synthesis.
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PEG4 Spacer: Enhances solubility, hydrophilicity, and steric accessibility.
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Orthogonal Functionality: Supports protected, modular conjugation strategies.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Immunology Research: Builds DNP-based haptens for antibody assays.
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Probe Development: Creates multifunctional, protected probes.
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Drug Delivery: Provides PEGylated scaffolds with controlled deprotection.
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Synthetic Chemistry: Useful as an intermediate in linker and polymer design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature ester cleavage.
This product combines antibody-recognized DNP functionality with orthogonal ester protection in a PEG4 scaffold, specifically offering solubility and flexibility for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
