Chlorambucil
This product is a nitrogen mustard derivative and alkylating agent widely used in cancer research and therapy. It contains a bis(2-chloroethyl)amine functional group that forms covalent bonds with DNA, specifically leading to crosslinking and inhibition of cell replication.
Key Features and Benefits
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Alkylating Agent – Covalently modifies DNA, causing crosslinks and strand breaks.
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Nitrogen Mustard Derivative – Provides potent cytotoxic activity through DNA alkylation.
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Research-Grade Purity – Suitable for oncology research, mechanistic studies, and drug development.
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Orally Bioavailable – Historically used in clinical treatment for hematological malignancies.
Applications
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Research on DNA damage and repair mechanisms
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Studies of apoptosis and cancer cell biology
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Development of anticancer drugs and analogs
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Preclinical oncology research models
Storage & Handling
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Storage: Store at –20 °C in a dry, tightly sealed container, protected from light.
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Use: Handle with caution in a chemical fume hood using proper protective equipment. Prepare fresh solutions as required.
This product is a nitrogen mustard alkylating agent that crosslinks DNA, inhibiting replication and promoting apoptosis. It remains an especially valuable research tool in oncology and drug development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
