Cbz-N-Amido-PEG6-acid linker contains a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond. The PEG spacer increases the aqueous solubility of the resulting compound. Cbz-amine can be deprotected by acidic conditions or hydrogenation.
Cbz-N-Amido-PEG6-acid is a polyethylene glycol (PEG) derivative that is used as a linker molecule to attach other molecules to it. It is an amino-PEG derivative, meaning it has an amino group attached to its PEG backbone, and it has a carboxyl group, which is a type of acid, attached to its end. This makes it useful for linking molecules together, as the carboxyl group can react with other molecules to form covalent bonds.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
