Boc-HyNic-PEG2-Amino-DBCO CAS: 2739801-63-7 contains a Boc protected HyNic group and a DBCO end group. The HyNic hydrzine moiety easily conjugate with aldehyde group and ketone group to form a reversible hydrazone linker, making it an ideal tool for carbonyl labelling. DBCO on the other hand readily react with azide bearing biomolecule through a copper-free click reaction instantly and in high yield. The PEG spacer increase the solubility of the resulting complex in aqueous media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.