Bis-PEG5-t-butyl ester
This product is a symmetric PEG linker featuring two t-butyl esters as acid-labile protecting groups connected by a PEG5 spacer. The PEG5 chain enhances solubility, flexibility, and spacing, while the protected esters allow controlled deprotection for orthogonal conjugation and multi-step synthesis.
Key Features and Benefits:
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Dual t-Butyl Esters: Provide acid-labile protection for controlled deprotection.
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PEG5 Spacer: Improves solubility, hydrophilicity, and steric accessibility.
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Symmetric Design: Supports balanced dual anchoring or crosslinking strategies.
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Orthogonal Chemistry: Enables stepwise functionalization in synthetic workflows.
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High Purity: Ensures reproducibility in bioconjugation and advanced synthesis.
Applications:
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Bioconjugation: Supports orthogonal coupling strategies with controlled release.
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Drug Delivery: Facilitates PEGylated linkers for enhanced solubility and stability.
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Synthetic Chemistry: Intermediate for orthogonal multi-step synthesis.
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Material Science: Functionalizes polymers, nanoparticles, or scaffolds with precision.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature deprotection.
This product combines PEG hydrophilicity with dual protected esters, offering especially versatile use in multi-step synthesis, drug delivery, and advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
