5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy, 9H-fluoren-9-ylmethyl ester CAS:868594-44-9 is a chemical compound that contains several functional groups, including an azide group, a hydroxyl group, and a fluorenylmethyloxycarbonyl (Fmoc) group.
In bioconjugation is commonly used as a linker for the conjugation of biomolecules such as proteins or peptides. The azide group can react with terminal alkynes or cyclooctynes, forming stable triazole linkages between the biomolecules. The PEG3 (triethylene glycol) chain improves the solubility and biocompatibility of the biomolecules, while the Fmoc group acts as a protecting group for the hydroxyl group, preventing unwanted reactions during the conjugation process.
In addition to bioconjugation has also been used in the development of drug delivery systems. The PEG3 chain can enhance the pharmacokinetics of drugs, while the azide group can be used to attach targeting ligands or imaging agents for specific drug delivery to target cells or tissues.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.