Bis-PEG17-NHS Ester (CAS: 2221948-93-0, 1008402-79-6) is a highly versatile compound widely used in bioconjugation, drug development, and molecular research. It features a 17-unit PEG spacer and an NHS ester group, allowing for efficient conjugation with amines. Therefore, it is ideal for protein labeling, antibody-drug conjugates, and various molecular applications.
Key Features:
- PEG17 Spacer: The 17-unit PEG spacer enhances solubility and flexibility. Consequently, it improves conjugation efficiency in both aqueous and biological settings.
- NHS Ester Group: The NHS ester reacts selectively with amine groups. As a result, it enables easy attachment of biomolecules such as proteins, peptides, and nucleic acids.
- High Purity: This compound ensures consistent and reliable results, which are essential for both research and industrial applications.
- Water Soluble: It dissolves well in aqueous and polar solvents. Thus, it offers flexibility for a variety of experimental setups.
- Biocompatible: The PEG spacer significantly improves biocompatibility, making it suitable for in vivo applications.
Applications:
- Bioconjugation: It is perfect for linking peptides, proteins, antibodies, and other biomolecules. Therefore, it is ideal for therapeutic and diagnostic purposes.
- Drug Development: The compound is crucial for creating antibody-drug conjugates (ADCs) and targeted therapies. This enhances drug delivery efficiency and efficacy.
- Protein Labeling: It plays an important role in tagging proteins with fluorescent or functional groups, allowing for easy detection and tracking.
- Polymer Chemistry: Bis-PEG17-NHS Ester is also used to create PEG-based drug delivery systems and nanomedicine applications, improving therapeutic outcomes.
- Surface Modification: Moreover, it can modify surfaces like nanoparticles, microarrays, and biosensors, making it useful for diagnostic and sensing applications.
Conclusion:
In conclusion, Bis-PEG17-NHS Ester (CAS: 2221948-93-0, 1008402-79-6) is a key compound in bioconjugation and drug development. Thanks to its PEG17 spacer and NHS ester group, it enables efficient conjugation, making it perfect for protein labeling, drug delivery, and advanced research. With its excellent solubility, biocompatibility, and high purity, this compound is a reliable choice for various scientific applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
