Biotin-PEG6-NH-Mal
Biotin-PEG6-NH-Mal is a high-purity heterobifunctional PEG linker featuring a biotin moiety for high-affinity avidin/streptavidin binding and a maleimide group for selective thiol conjugation. The PEG6 spacer enhances solubility, flexibility, and reduces steric hindrance, enabling especially efficient coupling in both aqueous and organic systems.
Key Features
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Biotin group for strong and specific avidin/streptavidin interactions
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Maleimide group for selective reaction with thiol-containing molecules
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PEG6 spacer improves hydrophilicity, reduces aggregation, and increases molecular flexibility
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High chemical stability and purity
Applications
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Protein, peptide, and antibody biotinylation via thiol–maleimide chemistry
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Avidin/streptavidin-based assay and detection systems
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Nanoparticle and surface functionalization
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Drug delivery and biomaterial engineering
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Biosensor development and affinity purification
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Bring to room temperature before opening
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Avoid repeated freeze–thaw cycles
This product contains a biotin group for avidin/streptavidin binding and a maleimide for thiol conjugation, with a PEG6 spacer specifically for enhanced solubility and reduced steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
