Biotin-PEG3-amine
This product is a heterobifunctional PEG3 linker with a biotin moiety and a terminal primary amine. The PEG3 spacer provides hydrophilicity and flexibility, while the biotin enables high-affinity binding to avidin/streptavidin systems, making it an excellent tool for targeted labeling, affinity capture, and bioconjugation.
Key Features and Benefits:
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Biotin Group: Strong affinity binding to avidin and streptavidin proteins.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and electrophiles.
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PEG3 Spacer: Provides compact hydrophilicity with reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Functionality: Combines biotin affinity with amine-based reactivity.
Applications:
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Affinity Labeling: Biotinylation of proteins, peptides, and biomolecules.
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Bioconjugation: Dual-functional linker for targeted labeling strategies.
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Drug Delivery: PEGylated linker enhances solubility and targeting ability.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and biosensors.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve amine reactivity.
This product combines strong biotin binding with amine-based conjugation in a compact PEG spacer, making it especially versatile for biomolecule labeling and targeted delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
