Biotin-PEG2-azide
Biotin-PEG2-azide is a high-purity PEG linker with a biotin for high-affinity avidin/streptavidin binding and an azide for bioorthogonal click chemistry (CuAAC or SPAAC). The PEG2 spacer enhances solubility, flexibility, and accessibility, enabling efficient bioconjugation in both aqueous and organic systems. This design is especially ideal for applications requiring precise biomolecule labeling, surface modification, and targeted delivery.
Key Features and Benefits
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Biotin Group: Enables strong, specific binding to avidin and streptavidin.
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Azide Group: Compatible with CuAAC and SPAAC click chemistry.
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PEG2 Spacer: Improves water solubility, flexibility, and reduces steric hindrance.
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High Purity: Supplied at >95% purity for reliable and reproducible performance.
Applications
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Biotinylation of biomolecules for affinity capture and detection.
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Surface and nanoparticle functionalization.
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Development of targeted drug delivery systems.
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Diagnostic probe and imaging agent preparation.
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Dual-functional labeling for research and diagnostics.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use anhydrous solvents; avoid moisture to preserve azide reactivity.
This product offers strong biotin binding and azide click chemistry in a short PEG2 spacer, especially delivering excellent solubility and precision for multifunctional bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
