Biotin-LC-Hydrazide
This product is a biotinylation reagent featuring a long-chain (LC) spacer and a terminal hydrazide group for conjugation with aldehydes or ketones. Its design enhances solubility, reduces steric hindrance, and ensures strong biotin–avidin interactions, making it especially effective for labeling, detection, and enrichment applications.
Key Features and Benefits:
-
Biotin Moiety: Provides strong binding affinity to avidin and streptavidin.
-
Hydrazide Group: Couples with aldehydes and ketones to form stable hydrazone bonds.
-
LC Spacer: Improves solubility and accessibility while reducing steric effects.
-
Versatile Functionality: Supports biotinylation in a wide range of biomolecules.
-
High Purity: Ensures consistent, reproducible results in assays.
Applications:
-
Protein Labeling: Targets oxidized carbohydrates on glycoproteins.
-
Detection & Enrichment: Supports streptavidin-based pull-down and detection assays.
-
Probe Development: Useful for biotin-tagged probes in imaging and diagnostics.
-
Bioconjugation: Enables stable biomolecule conjugates for research and clinical use.
Storage and Handling:
-
Storage: Store at –20 °C, protected from light and moisture.
-
Handling: Use freshly prepared solutions; keep away from oxidizing conditions.
This product combines high-affinity biotin binding with aldehyde/ketone-reactive hydrazide chemistry, making it an especially versatile tool for labeling, detection, and bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
