Biotin (Hydroxyprolinol) CPG 1000 is a solid-phase support designed for introducing biotin at the 3′ end of oligonucleotides during synthesis. Its hydroxyprolinol-based linker ensures stable and efficient biotin incorporation, making it ideal for various labeling and detection applications.
Key Features:
- High Loading Capacity: Optimized for long oligonucleotide synthesis (up to 120 bases).
- Hydroxyprolinol Linker: Provides stable biotin attachment.
- Pore Size: 1000 Å, suitable for large oligonucleotides.
- DMT Protection: Dimethoxytrityl (DMT) group for easy purification.
- Biocompatibility: Ensures minimal degradation during synthesis.
Applications:
- Oligonucleotide Synthesis: Incorporating biotin at the 3′ terminus.
- Nucleic Acid Labeling: For applications in molecular biology assays.
- Biotin-Avidin/Biotin-Streptavidin Systems: Enhancing detection sensitivity.
- Diagnostics and Biosensors: Used in probe-based diagnostic tests.
- Drug Development: For creating biotin-labeled therapeutic probes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
