Azido-PEG36-acid
This product is a long-chain PEG36 linker with a terminal azide for click chemistry and a carboxylic acid for amide coupling. The extended PEG36 spacer provides excellent hydrophilicity, flexibility, and long-range spacing, making it especially suitable for bioconjugation, drug delivery, and advanced material applications.
Key Features and Benefits:
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Azide Group: Enables CuAAC and SPAAC click chemistry with alkynes.
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Carboxylic Acid Group: Couples efficiently with amines for stable amide bond formation.
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PEG36 Spacer: Provides very long hydrophilic spacing, solubility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in demanding workflows.
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Dual Reactivity: Combines bioorthogonal click chemistry with classical amide coupling.
Applications:
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Click Chemistry: Supports bioorthogonal azide–alkyne ligation for labeling and conjugation.
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Bioconjugation: Facilitates long-range attachment of proteins, peptides, and biomolecules.
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Drug Delivery: PEGylated linker improves solubility, circulation time, and targeting.
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Surface Functionalization: Functionalizes nanoparticles, polymers, hydrogels, and biosensors.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide and acid stability.
This product combines click-ready azide functionality with carboxyl reactivity in a very long PEG chain, making it an especially versatile reagent for advanced conjugation and drug delivery designs.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
