Azido-PEG3-(CH2)3OH
This product is a heterobifunctional PEG linker containing a terminal azide, a PEG3 spacer, and a propanol group. The azide reacts in copper-catalyzed (CuAAC) or copper-free (SPAAC) click chemistry with alkynes, while the hydroxyl group provides a versatile handle for further derivatization. The PEG3 chain enhances solubility and flexibility, making this reagent especially useful for probe development, drug delivery, and bioconjugation.
Key Features and Benefits
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Azide Group: Performs CuAAC or SPAAC click chemistry with alkynes.
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Hydroxyl Group: Provides a modifiable handle for additional chemistry.
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PEG3 Spacer: Improves solubility and reduces steric hindrance.
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Compact Design: Offers balance between spacing and reactivity.
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High Purity: Produced to ≥95% purity for consistent performance.
Applications
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Bioconjugation: Links azide- and hydroxyl-reactive partners.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Serves as a modular linker for therapeutic systems.
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Polymer and Material Science: Introduces functional PEG groups into polymers.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Use freshly prepared solutions; avoid repeated freeze–thaw cycles.
This product integrates click-ready azide chemistry with hydroxyl versatility in a PEG3 scaffold, specifically providing flexibility for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
