Azido-PEG2-PFP ester
Azido-PEG2-PFP ester is a high-purity bifunctional PEG reagent with an azide and a pentafluorophenyl (PFP) ester linked by a PEG2 spacer, specifically enabling amine coupling via the PFP ester and click chemistry via the azide.
Key Features and Benefits
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Azide Group – Enables selective and efficient click chemistry with alkynes via CuAAC or strain-promoted cycloaddition.
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PFP Ester Group – Highly reactive toward amines for stable amide bond formation.
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PEG2 Spacer – Provides hydrophilicity, reduced steric hindrance, and flexible linker length.
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High Purity – Ensures reproducible results in conjugation, labeling, and biorthogonal applications.
Applications
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Dual conjugation strategies involving amine coupling and click chemistry
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Protein, peptide, or antibody modification
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Probe, drug, and polymer conjugation
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Surface and nanoparticle functionalization
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid moisture and repeated freeze–thaw cycles.
This product provides orthogonal reactivity with an azide group for click chemistry and a PFP ester for amine coupling, offering a versatile PEG2 linker specifically for bioconjugation, labeling, and materials functionalization.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
