APN-PEG4-BCN(exo) is an advanced bifunctional linker comprised of a stable, exocyclic alkyne-functionalized bicyclononyne (BCN) moiety and an aminooxypropyl (APN) group, connected by a polyethylene glycol (PEG4) spacer. This versatile linker is designed for click chemistry applications, providing bioorthogonal reactivity, enhanced water solubility, and reduced non-specific binding, making it an ideal candidate for various pharmaceutical research and development processes.
Introduction to the application in pharmaceutical R&D:
APN-PEG4-BCN(exo) has emerged as a valuable tool in pharmaceutical research and development, particularly in the field of targeted drug delivery. Its bioorthogonal reactivity enables the selective conjugation of therapeutic agents to biomolecules such as antibodies, peptides, or nucleic acids. This targeted approach enhances the efficacy and safety profiles of drugs, reducing off-target effects and improving pharmacokinetics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
