Aminooxy-PEG3-azide (CAS: 1306615-51-9) is a bifunctional linker with an aminooxy group and an azide group connected by a PEG3 spacer. The aminooxy group reacts with aldehydes to form oxime bonds, while the azide group supports click chemistry (CuAAC) with alkynes. Its PEG3 spacer improves water solubility and flexibility.
Key Features:
- Functional Groups: Aminooxy for oxime ligation and azide for CuAAC reactions
- Molecular Formula: C₈H₁₈N₄O₄
- Molecular Weight: 234.26 g/mol
- Purity: Typically ≥95%
Applications:
- Bioconjugation: Enables efficient linking of biomolecules through oxime ligation and click chemistry.
- Antibody-Drug Conjugates (ADCs): Functions as a stable linker in ADC synthesis.
- PROTAC Development: Acts as a PEG-based linker for synthesizing proteolysis-targeting chimeras (PROTACs).
- Surface Modification: Functionalizes surfaces for immobilizing biomolecules in biosensors and bioassays.
This versatile linker is ideal for applications in drug development, diagnostics, and chemical biology research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
