Amino-PEG25-acid
This product is a bifunctional PEG25 linker with a primary amine and a terminal carboxylic acid. The long PEG25 spacer provides excellent hydrophilicity, extended flexibility, and wide spacing, making it especially versatile for bioconjugation, drug delivery, and advanced material modification.
Key Features and Benefits:
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Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
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Carboxylic Acid Group: Reacts with primary amines to form stable amide bonds.
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PEG25 Spacer: Provides long hydrophilic spacing, solubility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Supports orthogonal, multistep, and multifunctional conjugation.
Applications:
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Bioconjugation: Attaches proteins, peptides, and biomolecules with extended PEG spacing.
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Drug Delivery: PEGylated linker improves solubility, circulation, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and biomaterials.
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Material Science: Ideal for PEGylated scaffolds and advanced polymer design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve amine and acid reactivity.
This product combines long PEG spacing with dual reactive groups, making it an especially powerful reagent for orthogonal synthesis, conjugation, and drug delivery strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
