Alkyne-polysarcosine40 (Alkyne-pSar₄₀)
- Full Name: Alkyne-terminated Polysarcosine, DP = 40
- Appearance: White to off-white lyophilized powder
- Solubility: Soluble in water, DMSO, DMF
- Key Features:
- Nonionic biodegradable polypeptoid composed of sarcosine (N-methylglycine) units
- Terminal alkyne group for CuAAC / SPAAC click chemistry with azide-modified molecules
- Excellent stealth effect, protein-resistant, low cytotoxicity and non-immunogenic
- Widely studied as biodegradable alternative to PEG
- Main Applications:
- Bioorthogonal bioconjugation for nanoparticle surface modification
- Stealth coating for drug delivery carriers
- Fabrication of hydrogels and polymer micelles
- Biomaterial engineering and bioimaging probes
- Storage: −20 °C, desiccated, protect from light and moisture
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
