4-Arm PLGA-COOH, MW 40K is a branched, biodegradable PLGA polymer with four terminal carboxylic acid groups while its multivalent architecture specifically supports bioconjugation, crosslinking, drug delivery, polymer modification, and functional biomaterial development.
Key Features and Benefits
- 4-Arm Architecture: Provides four PLGA arms for multivalent functionalization and network formation.
- Carboxyl Functionalization: Supplies terminal COOH groups for conjugation and further chemical modification.
- MW 40K: Supports durable polymer networks, particle formulation, and controlled-release applications.
- Reactive COOH Groups: Enable amine coupling after activation with standard carbodiimide chemistry.
- Multivalent Platform: Four reactive termini support efficient conjugation, crosslinking, and multifunctional polymer modification.
- Biodegradable: The PLGA segments undergo hydrolytic degradation into lactic acid and glycolic acid.
Applications
- Bioconjugation: Enables attachment of peptides, proteins, targeting ligands, and other amine-containing molecules.
- Crosslinking: Supports biodegradable polymer networks using complementary reactive components.
- Drug Delivery: Supports functional carriers, nanoparticles, microparticles, and controlled-release systems.
- Polymer Modification: Provides multiple COOH groups for introducing linkers, ligands, and functional molecules.
- Biomaterials: Enables development of hydrogels, scaffolds, coatings, matrices, and other biodegradable systems.
Storage and Handling
- Storage: Store at –20 °C in a fully sealed container under dry and dark conditions.
- Handling: Protect from moisture, light, and excessive heat to maintain polymer integrity and functionality.
4-Arm PLGA-COOH, MW 40K combines biodegradable PLGA with four reactive carboxyl termini while its branched structure specifically supports multivalent bioconjugation, crosslinking, drug delivery, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.