3-(2-Pyridyldithio)propionic Acid (PDPA, CAS 68181-17-9) is a heterobifunctional crosslinker with a carboxyl group (-COOH) and a pyridyl disulfide moiety. It enables thiol-disulfide exchange for reversible bioconjugation, widely used in protein modification, antibody-drug conjugates (ADCs), PROTAC linker synthesis, and peptide labeling. White solid, soluble in DMSO/DMF, stored at <0°C under inert gas.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
