Biotin-PEG4-Azide
This product is a heterobifunctional linker featuring a biotin group for high-affinity avidin/streptavidin binding and a terminal azide for click chemistry. The PEG4 spacer provides solubility, flexibility, and steric accessibility, making it especially effective for probe design, drug delivery, and bioconjugation.
Key Features and Benefits:
-
Biotin Moiety: Provides strong and specific binding to avidin/streptavidin systems.
-
Azide Group: Supports CuAAC or SPAAC click chemistry with alkynes.
-
PEG4 Spacer: Improves solubility and reduces steric hindrance.
-
Dual Functionality: Combines biotin affinity with bioorthogonal reactivity.
-
High Purity: Ensures reproducibility in sensitive workflows.
Applications:
-
Probe Development: Builds biotinylated, click-reactive probes for imaging and diagnostics.
-
Drug Delivery: Supports PEGylated scaffolds with avidin-targeting handles.
-
Bioconjugation: Links biomolecules through biotin capture and click chemistry.
-
Material Science: Functionalizes surfaces and nanoparticles with dual reactivity.
Storage and Handling:
-
Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
-
Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve reactivity.
This product integrates biotin binding with azide reactivity in a PEG4 scaffold, specifically offering versatility for multifunctional conjugation, probe design, and drug delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
