AxisPharm offers various target specific probes, such as folate PEG, biotin PEG, PROTAC PEG, fluorescent dye probes, and image probes.
Probes are a class of chemical compounds that contain functional groups designed to selectively interact with biological molecules, such as enzymes, receptors, and nucleic acids. These functional groups include fluorescent dyes, biotin, and affinity tags, among others, which allow for the detection and quantification of specific molecules in complex biological systems.
In pharmaceutical research and development, probes play a critical role in the identification and validation of potential drug targets, as well as in the screening and characterization of drug candidates. For example, fluorescent probes can be used to visualize and monitor protein-protein interactions, enzyme activity, and intracellular signaling pathways, providing insights into the underlying mechanisms of disease and drug action.
In addition to their use in basic research, probes are also valuable tools in drug discovery and development. They can be used to screen large compound libraries for molecules that interact with a specific target, identify potential off-target effects, and assess drug efficacy and toxicity in vivo.