Mal-PEG-HZ(Maleimide-PEG-Hydrazide) contains two functional groups, a maleimide group and a hydrazide group, attached to either end of a PEG chain. Maleimide is a highly reactive functional group that readily reacts with thiol groups via Michael addition, while hydrazide can react with aldehydes and ketones via hydrazone formation.
Maleimide-PEG-Hydrazide has found numerous applications in the field of pharmaceutical research and development, particularly in the area of drug conjugation.
