Name: m-PEG8-Norbornene
SKU: AP10569
Availability: InStock

m-PEG8-Norbornene

$280.00 – $1,470.00

m-PEG8-Norbornene is a high-purity PEG linker with a norbornene for thiol–ene click chemistry and a methoxy end group specifically for stability. The PEG8 spacer specifically improves solubility and flexibility for efficient conjugation.

Unit

Price

Quantity

100 mg

$280

250 mg

$560

500 mg

$980

$1470

Would you like to inquire about bulk pricing?

m-PEG8-Norbornene

m-PEG8-Norbornene is a high-purity monofunctional PEG linker with a norbornene group for thiol–ene click chemistry and a methoxy terminal for stability and reduced non-specific interactions. The PEG8 spacer provides excellent water solubility, flexibility, and low steric hindrance, enabling efficient photoinitiated or radical-mediated conjugation in both aqueous and organic systems. This design is ideal for bioorthogonal labeling, hydrogel formation, surface modification, and polymer crosslinking.

Key Features and Benefits

Norbornene Group: Reacts efficiently with thiols under UV or radical initiation for thiol–ene click chemistry.
Methoxy Terminal: Inert end group that reduces undesired side reactions and non-specific binding.
PEG8 Spacer: Enhances solubility, flexibility, and accessibility of the norbornene group.
Photoclick Capability: Suitable for light-triggered conjugations in mild, aqueous conditions.
High Purity: Supplied at >95% purity for reliable and reproducible performance.

Applications

Hydrogel Formation: Crosslink PEG-based or thiol-containing polymers via thiol–ene chemistry.
Surface Functionalization: Introduce norbornene groups for subsequent thiol coupling.
Bioorthogonal Labeling: Conjugate thiol-containing biomolecules without affecting other functional groups.
Polymer Crosslinking: Enable spatial and temporal control in material assembly.
Drug Delivery Systems: Create norbornene-functionalized carriers for controlled release applications.

Storage and Handling

Storage: Store at –20 °C, dry, and protected from light.
Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture to maintain reactivity.

m-PEG8-Norbornene combines a norbornene click chemistry handle with a hydrophilic PEG8 spacer and inert methoxy terminus, offering excellent solubility and reactivity specifically for bioorthogonal conjugation, hydrogel formation, and advanced material applications.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.