HO-PEG7-CH2COOtBu
This product is a high-purity PEG derivative featuring a terminal hydroxyl group and a tert-butyl protected carboxymethyl group, connected through a PEG7 spacer for excellent solubility and flexibility.
Key Features and Benefits
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Hydroxyl Group – Provides a reactive handle for further functionalization via esterification, etherification, or coupling reactions.
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t-Butyl Protected Carboxymethyl Group – Acid-labile protecting group that can be selectively cleaved to yield a free carboxylic acid for conjugation.
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PEG7 Spacer – Enhances solubility, minimizes steric hindrance, and improves accessibility in conjugation workflows.
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High Purity – Suitable for demanding applications in bioconjugation, polymer synthesis, and drug delivery.
Applications
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Intermediate for synthesis of PEGylated biomolecules
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Scaffold for bioconjugation and surface modification
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Precursor for polymer–drug conjugates and advanced materials
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Versatile linker in diagnostic and therapeutic development
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DCM, DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product provides a hydroxyl group and a tert-butyl protected carboxymethyl group on a PEG7 spacer, delivering solubility, flexibility, and a versatile platform specifically for bioconjugation and functionalization.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
