Cbz-N-Amido-PEG4-acid
This product is a bifunctional PEG4 linker with a Cbz-protected amide and a terminal carboxylic acid. The PEG4 spacer provides solubility and flexibility, while the Cbz group offers stable carbamate protection for orthogonal, stepwise synthesis.
Key Features and Benefits:
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Cbz-Protected Amide: Provides stable protection for controlled deprotection.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG4 Spacer: Enhances hydrophilicity and reduces steric hindrance in conjugation.
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High Purity: Ensures reproducible performance in research and synthesis workflows.
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Orthogonal Reactivity: Supports selective and stepwise conjugation strategies.
Applications:
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Bioconjugation: Conjugate biomolecules with controlled PEG spacing.
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Drug Delivery: Improves solubility and pharmacokinetic profiles of payloads.
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Surface Modification: Functionalize nanoparticles, hydrogels, or polymers.
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Material Science: Integrate into PEGylated scaffolds for advanced materials.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve reactivity.
This product provides a short PEG spacer with Cbz-protected and acid functionalities, making it an especially versatile reagent for orthogonal conjugation and controlled synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
