t-Boc-N-Amido-PEG7-acid
This product is a bifunctional PEG7 linker with a Boc-protected amide and a terminal carboxylic acid. The PEG7 spacer improves hydrophilicity and flexibility, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Stable, acid-labile protection for selective deprotection.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG7 Spacer: Provides moderate hydrophilicity, flexibility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in bioconjugation workflows.
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Orthogonal Reactivity: Supports multistep and controlled synthesis.
Applications:
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Bioconjugation: Enables precise protein, peptide, and biomolecule linking.
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Drug Delivery: PEGylated linker enhances solubility and pharmacokinetics.
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Surface Modification: Functionalizes nanoparticles, hydrogels, or polymers.
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Material Science: Useful for PEGylated scaffolds in advanced materials.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and acid integrity.
This product provides a mid-length PEG spacer with Boc protection and a carboxyl group, making it an especially versatile reagent for orthogonal conjugation and synthetic workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
