PLLA-PEG-Biotin (PLLA-PEG-BIO), MW x 5K, n 1K combines a 5K poly(L-lactide) (PLLA) segment, 1K PEG segment, and terminal biotin functionality. This biodegradable amphiphilic block copolymer specifically supports biotin-mediated conjugation, nanoparticle functionalization, drug delivery research, and biomaterial development.
Key Features and Benefits
- Block Copolymer Structure: Combines hydrophobic PLLA with hydrophilic PEG for amphiphilic polymer design and functionalization research.
- PLLA MW 5K: The 5K PLLA segment specifically provides a biodegradable hydrophobic component for polymer assembly and material development.
- PEG MW 1K: The 1K PEG segment provides a compact hydrophilic spacer for polymer functionalization and formulation studies.
- Biotin Functionality: Terminal biotin enables strong noncovalent interactions with avidin, streptavidin, and related biotin-binding proteins.
- High-Affinity Binding: Biotin-streptavidin interactions support stable molecular recognition and assembly in research applications.
- Amphiphilic Character: PLLA and PEG provide distinct hydrophobic and hydrophilic regions that specifically support self-assembly in suitable environments.
- Biodegradable Polymer Platform: PLLA provides a biodegradable polyester component for polymer-based delivery and biomaterial research.
- Functional Surface Design: The biotin end group specifically supports affinity-based modification of nanoparticles, polymer assemblies, and biomaterial surfaces.
Applications
- Biotin-Avidin Research: Supports affinity-based interactions with avidin, streptavidin, and related binding systems.
- Bioconjugation: Enables biotin-mediated attachment of compatible proteins, ligands, probes, and other biomolecules.
- Nanoparticle Functionalization: Useful for adding biotin functionality to biodegradable polymeric nanoparticles and related assemblies.
- Ligand Attachment: Supports indirect incorporation of streptavidin-linked ligands and functional molecules.
- Polymeric Micelles: Amphiphilic PLLA and PEG blocks support research into self-assembled polymer structures.
- Drug Delivery Research: Supports development of functionalized biodegradable polymer-based delivery systems.
- Surface Modification: Biotin functionality enables affinity-based modification of appropriately designed polymer and biomaterial surfaces.
- Biomaterial Research: Supports development of biodegradable PEG-containing materials with biotin-mediated recognition capabilities.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
PLLA-PEG-Biotin (PLLA-PEG-BIO), MW x 5K, n 1K combines biodegradable PLLA with a compact PEG spacer and terminal biotin functionality, while its PLLA-rich architecture supports affinity-based conjugation, nanoparticles, drug delivery, and functional biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.