Poly(L-lactide)(PLLA), MW 500-700K is a high-molecular-weight biodegradable polyester derived from L-lactide. Its stereoregular polymer structure provides crystallinity, mechanical strength, and relatively slow degradation, making it especially suitable for biomaterials, tissue engineering, scaffold fabrication, controlled drug delivery, and polymer research.
Key Features and Benefits
- High Molecular Weight: The 500-700K molecular weight range supports high chain entanglement, mechanical integrity, and formation of durable polymer structures.
- Biodegradable Polyester: PLLA undergoes hydrolytic degradation of its ester backbone, specifically producing lower-molecular-weight degradation products.
- Stereoregular Polymer Structure: The L-lactide-derived structure promotes crystallinity and provides useful thermal and mechanical properties.
- Mechanical Strength: High-molecular-weight PLLA provides structural strength and stiffness for applications requiring mechanically stable polymer matrices.
- Slow Degradation Profile: The high molecular weight and semicrystalline structure support relatively slow degradation compared with many lower-molecular-weight biodegradable polymers.
- Processable Polymer: Supports fabrication into films, fibers, porous scaffolds, particles, and other polymer structures using appropriate processing methods.
- Biomaterial Platform: Provides a versatile biodegradable polymer matrix specifically for biomedical materials, tissue engineering, controlled release, and polymer development.
Applications
- Tissue Engineering: Supports fabrication of biodegradable scaffolds and matrices for tissue engineering research.
- Scaffold Fabrication: Suitable for porous scaffolds, fibers, membranes, films, and other three-dimensional polymer structures.
- Drug Delivery: Supports development of biodegradable matrices and controlled-release drug-delivery systems.
- Controlled Release: Provides a slowly degrading polymer matrix for sustained-release formulation research.
- Electrospinning: Suitable for preparation of high-molecular-weight PLLA fibers and fibrous scaffolds.
- Polymer Processing: Supports research involving solvent casting, extrusion, molding, and other compatible polymer-processing techniques.
- Biomaterial Research: Supports development of biodegradable medical materials, polymer composites, coatings, and related biomaterial systems.
Storage and Handling
- Storage: Store in a tightly sealed container under cool, dry conditions. For long-term storage, keep the material protected from moisture and excessive heat.
- Handling: Protect from moisture because hydrolysis can reduce polymer molecular weight. Dry the polymer appropriately before melt processing or other moisture-sensitive applications.
This product provides a high-molecular-weight biodegradable polyester with mechanical strength, crystallinity, processability, and relatively slow degradation. It specifically supports scaffold fabrication, tissue engineering, controlled drug delivery, electrospinning, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.