PLGA Cy5 Capped, MW 5K is a medium-molecular-weight, Cy5-terminated fluorescent biodegradable PLGA copolymer designed for deep-red fluorescence imaging, high-sensitivity biological tracing, and sustained drug delivery carrier research. It supports customizable molecular weight and full-range PLGA composition ratios, providing flexible formulation solutions for diverse in vitro and in vivo biomedical imaging applications.
Basic Specifications
Alternative Name: Cyanine 5-PLGA, Cy5-PLGA
PLGA Composition: 50:50, 65:35, 75:25, 85:15, Custom
Molecular Weight: 5K, Custom
Appearance: Blue to dark blue or purple solid
Key Features and Benefits
Cy5 Fluorescent Capped: Terminal Cy5 fluorophore modification provides stable deep-red fluorescence with low background interference and strong tissue penetration. It enables high-sensitivity real-time tracing and quantitative detection without additional staining, ideal for in vivo deep-tissue imaging.
Versatile PLGA Ratio Options: Covers mainstream 50:50, 65:35, 75:25, 85:15 ratios and fully customized formulations. Precisely adjusts polymer hydrophilicity, degradation kinetics and particle morphology to match different sustained-release and imaging scenarios.
Customizable Medium Molecular Weight: Standard 5K molecular weight balances excellent solubility, moderate degradation rate and structural stability. Custom MW service further adapts to personalized formulation requirements from rapid release to long-term sustained release.
Excellent Biocompatibility & Biodegradability: Fully biocompatible and non-toxic under physiological conditions, gradually hydrolyzing into lactic acid and glycolic acid. It ensures high biosafety for biological imaging and biomedical carrier research.
Stable Fluorescence Performance: Reliable terminal capping effectively avoids fluorophore shedding and fluorescence quenching, maintaining consistent and high-sensitivity fluorescent signals during particle preparation, storage and biological degradation.
Applications
High-Sensitivity Biological Tracing: Suitable for deep-tissue in vitro and in vivo tracking of PLGA nanoparticles and microspheres, achieving low-background fluorescent imaging analysis.
Sustained Drug Delivery Imaging: Enables visual monitoring of medium-term drug carrier release behavior, in vivo accumulation, circulation metabolism and retention efficiency for sustained-release formulation development.
Biomedical Fluorescent Labeling: Acts as a high-performance self-fluorescent polymer matrix for degradable biomaterial labeling, biological distribution research and optical imaging analysis.
Custom Formulation Research: Supports personalized material design and advanced carrier preparation based on adjustable molecular weight and multi-ratio PLGA composition.
Storage and Handling
Storage: Store at –20 °C in a sealed, dry, light-proof and moisture-proof container.
Handling: Avoid strong light exposure, repeated freeze-thaw cycles and high-temperature environments to prevent fluorescence quenching and premature polymer hydrolysis.
PLGA Cy5 Capped, MW 5K combines tunable medium molecular weight, multi-ratio degradable performance, and high-penetration Cy5 deep-red fluorescence, professionally applied for high-sensitivity biological tracing, sustained drug delivery imaging and customized biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.