OPSS‑Poly(L‑Lysine), MW 3.3 kDa (also OPSS‑PLL, Pyridylthio‑PLL):
- A cationic polyamino acid (poly‑L‑lysine) with orthopyridyl disulfide (OPSS) end‑capping, MW ≈ 3 300 Da (≈ 20 lysine units).
- Water‑soluble crystalline solid; positively charged backbone binds anionic biomolecules (DNA/RNA, cell membranes).
- OPSS enables selective reaction with thiols (‑SH) to form reversible disulfide bonds.
- Used in bioconjugation, gene/drug delivery, cell adhesion, surface functionalization, and layer‑by‑layer assembly.
- Typically supplied as solid (≥ 90% purity) for research use only; store at ‑20 °C.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.