RH 237 Product Overview
RH 237, N-(4-sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, CAS: 83668-91-1, is a voltage-sensitive dye used for imaging membrane potential in neurons, heart cells, and mitochondria.
Key Features:
- Fast-Response Potential-Sensitive Probe: Ideal for real-time monitoring of membrane potential changes.
- Versatile Applications: Primarily used for imaging:
- Neurons: Membrane potential, synaptic activity, and ion channel function.
- Heart Cells: Electrical conduction and functional activity.
- Mitochondria: Assessing dynamic functional changes.
- Wavelength Properties:
- In Ethanol: Excitation/Emission Maxima at 532/777 nm.
- In Cell Membranes: Blue-shifted by ~20 nm (excitation) and ~80 nm (emission).
Applications:
- Neuroscience: Visualize synaptic activity and ion channel behavior.
- Cardiac Research: Investigate arrhythmias and electrical activity in heart cells.
- Mitochondrial Function: Track potential-sensitive mitochondrial dynamics.
- Electrophysiology: Study electrical activity in excitable cells.
- Live Cell Imaging: Real-time membrane potential tracking.
Usage Guidelines:
- Working Concentration: Start with 1-5 μM. Optimize experimentally for best results.
- Compatibility: Works with confocal, widefield, and live-cell imaging systems.
- Precautions: Adjust conditions to minimize phototoxicity and photobleaching.
For more details, consult the product datasheet or scientific literature.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
