Tetraglycine hydrochloride

Tetraglycine Hydrochloride, or Gly-Gly-Gly-Gly (CAS 38126-71-5) is an oligopeptide composed of four glycine units, terminated with amino (-NH₂) and carboxyl (-COOH) groups. This structure makes it a versatile bifunctional linker in various biochemical applications.

Key Features:

• Molecular Formula: C₈H₁₅ClN₄O₅
• Molecular Weight: 282.68 g/mol
• Functional Groups: Terminal amino and carboxyl groups
• Solubility: Soluble in water, DMSO, acetonitrile, and methanol

Tetraglycine Applications:

1. Bioconjugation:
   • The terminal amino group can react with activated esters, carbonyl compounds, and carboxylic acids, facilitating the attachment of various biomolecules.
2. Peptide Synthesis:
   • Serves as a building block in synthesizing longer peptides or as a spacer in peptide-based constructs.
3. Protein Modification:
   • Acts as a linker to modify proteins, aiding in the study of protein interactions and functions.

Tetraglycine Hydrochloride is a valuable reagent in chemical biology and pharmaceutical research, enabling the development of complex molecular assemblies and advanced therapeutics.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.