PySS-PEG-NHS is a cleavable linker for bioconjugation. It has a PySS group for thiol binding via disulfide bonds, a PEG2 spacer for better solubility and flexibility, and an NHS ester for efficient amine conjugation.
Key Features:
- PySS Group: Binds to thiol groups, forming cleavable disulfide bonds.
- PEG2 Spacer: Increases solubility and reduces steric hindrance.
- NHS Ester: Reacts with primary amines for stable attachment.
Applications:
- Protein and Peptide Conjugation: Attaches proteins or peptides to molecules or surfaces.
- Antibody-Drug Conjugates (ADCs): Links drugs to antibodies for targeted therapy.
- Surface Functionalization: Adds functional groups for biosensor and diagnostic applications.
Store at -20°C, and dissolve in DCM, THF, acetonitrile, DMF, or DMSO for use.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
