Azido-PEG3-SS-NHS

Azido-PEG3-SS-NHS, or N3-PEG3-SS-NHS, is a cleavable linker for bioconjugation. It includes an azide group for click chemistry, a PEG3 spacer for solubility and flexibility, a disulfide bond for cleavable linkage, and an NHS ester for amine conjugation.

Key Features:

• Azide Group (N3): Enables click reactions with alkynes.
• PEG3 Spacer: Improves solubility and reduces steric hindrance.
• Disulfide Bond (SS): Allows controlled release under reducing conditions.
• NHS Ester: Reacts with primary amines for stable attachment.

Applications:

• Antibody-Drug Conjugates (ADCs): Links drugs to antibodies for targeted therapy.
• Protein and Peptide Conjugation: Attaches proteins or peptides to surfaces.
• Surface Functionalization: Adds functional groups to surfaces for biosensors.

Store at -20°C and dissolve in DCM, THF, acetonitrile, DMF, or DMSO before use.