5′-ODMT cEt G Phosphoramidite (CAS: 945628-66-0) is a modified guanosine phosphoramidite used in oligonucleotide synthesis. It features a 5′-ODMT (dimethoxytrityl) protecting group and a cEt (constrained ethyl) modification, which enhances binding affinity, nuclease resistance, and stability of the resulting oligonucleotides. This makes it ideal for applications in antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutic research.
Applications:
- Oligonucleotide Synthesis: Incorporates cEt-modified guanosine for enhanced stability and binding.
- Therapeutic Development: Used in antisense oligonucleotides and siRNA for improved efficacy.
- Nucleic Acid Research: Increases oligonucleotide resistance to nucleases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
