Merocyanine Retinal Analog (MCRA)
This product is a synthetic chromophore designed to mimic the natural retinal cofactor of rhodopsins. It features a merocyanine scaffold that extends the conjugated π-system, specifically providing enhanced bathochromic shifts and stronger absorption in the visible and near-infrared range. MCRA is especially used in optogenetics, photobiology, and synthetic photoreceptor research to investigate light-driven protein function and design red-shifted optical tools.
Key Features and Benefits
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Chromophore Mimic: Functions as a retinal analog for rhodopsin-based systems.
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Merocyanine Scaffold: Provides extended conjugation for red-shifted absorption.
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Enhanced Optical Properties: Delivers stronger and tunable absorption in visible/NIR regions.
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Research-Grade Design: Optimized for optogenetics and photobiology applications.
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High Purity: Produced to ≥95% purity for consistent experimental results.
Applications
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Optogenetics: Reconstitutes rhodopsin-based tools with red-shifted responsiveness.
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Photobiology: Probes light-driven protein dynamics and signaling.
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Protein Engineering: Builds synthetic photoreceptors with extended absorption profiles.
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Imaging and Sensors: Serves as a chromophore in bio-inspired optical systems.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Protect from light; prepare fresh solutions before use.
This product combines extended conjugation with enhanced red-shifted absorption, specifically providing a versatile retinal mimic for optogenetics and photobiology research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
