MAC glucuronide linker, 1 CAS :2222981-71-5, Formula:C42H47N3O17S, is a cleavable linker used in the construction of antibody-drug conjugates (ADCs). It consists of a glucuronide moiety that can be selectively cleaved under specific conditions, releasing the attached drug payload. This linker design allows for targeted drug delivery, where the antibody specifically recognizes and binds to the target antigen, leading to internalization and subsequent release of the drug within the targeted cells. MAC glucuronide linker-1 provides a strategy to enhance the therapeutic efficacy and selectivity of ADCs in various applications, including cancer treatment.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.