Folate-PEG2 DBCO amide

Folate-PEG2-DBCO Amide Overview

Folate-PEG2-DBCO Amide combines a folate group, a PEG chain, and a DBCO (dibenzocyclooctyne) group. The folate group targets certain cancer cells by exploiting their folate uptake pathways. The PEG chain enhances solubility and biocompatibility, while the DBCO group reacts with azides to form stable triazole linkages, enabling attachment to other molecules or surfaces.

Key Features:

• Folate Group: Targets cancer cells that overexpress folate receptors.
• PEG Chain: Improves solubility and biocompatibility.
• DBCO Group: Reacts with azide groups for bioorthogonal click chemistry, allowing easy conjugation to other molecules.

Applications:

Folate-PEG2-DBCO Amide is used for targeted drug delivery, enhancing the pharmacokinetics and efficacy of drugs by selectively targeting cancer cells. Its combination of functional groups makes it ideal for developing targeted cancer therapies and other advanced therapeutics.