Mal-amido-PEG23-amine is a high-quality, bifunctional PEGylation reagent featuring a maleimide group and an amine group. The maleimide moiety selectively reacts with thiol-containing biomolecules, while the amine end-group facilitates conjugation to carboxylic acids. This specialized reagent is particularly useful in the design of advanced drug delivery systems and bioconjugates in pharmaceutical research.
Introduction to the Application:
In pharmaceutical research and development, Mal-amido-PEG23-amine serves as a versatile linker for creating targeted drug delivery systems and improving drug stability. By utilizing its bifunctional nature, it enables the covalent attachment of drugs, peptides, or proteins to diverse carriers, such as nanoparticles and antibodies. This PEGylation strategy enhances solubility, circulation time, and bioavailability, ultimately leading to better therapeutic outcomes and reduced side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.