TCO-ald is a chemical compound that contains several functional groups, including an aldehyde group and a tetrazine group. The aldehyde group is a highly reactive group that can participate in a wide range of chemical reactions, such as oxidation, reduction, and condensation reactions. The tetrazine group is also highly reactive and can participate in a specific type of chemical reaction called a bioorthogonal reaction.
In bioconjugation, TCO-ald can be used as a linker molecule to attach molecules to surfaces or other molecules via bioorthogonal reactions. Specifically, the tetrazine group in TCO-ald can react with molecules that contain a strained alkyne group, such as trans-cyclooctene (TCO), via a rapid and specific bioorthogonal reaction. This allows for the attachment of molecules to surfaces or other molecules in a highly specific and efficient manner, without interfering with other biological processes.
The use of TCO-ald in bioconjugation has numerous applications in fields such as drug delivery, imaging, and biosensing. For example, TCO-ald can be used to attach therapeutic molecules to surfaces or other molecules, enabling targeted drug delivery to specific cells or tissues. It can also be used to attach imaging agents to cells or tissues, allowing for the visualization and tracking of biological processes. Overall, the use of TCO-ald in bioconjugation represents an important advance in the development of novel biotechnologies and biomedical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
