Thiol-PEG4-alcohol
This product is a heterobifunctional linker featuring a thiol group for selective conjugation and a terminal hydroxyl group for further modification. The PEG4 spacer enhances solubility, flexibility, and steric accessibility, making it especially useful for bioconjugation, material science, and drug delivery.
Key Features and Benefits:
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Thiol Group: Enables selective conjugation with maleimides, gold, or disulfide exchange.
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Hydroxyl Group: Provides a modifiable handle for further activation.
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PEG4 Spacer: Improves solubility, hydrophilicity, and steric flexibility.
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Dual Functionality: Supports orthogonal conjugation strategies.
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High Purity: Ensures reliable performance in sensitive workflows.
Applications:
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Bioconjugation: Couples biomolecules via thiol and hydroxyl handles.
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Drug Delivery: Builds PEGylated, multifunctional carriers.
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Probe Development: Useful in diagnostic probe and imaging scaffold design.
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Material Science: Functionalizes nanoparticles, polymers, and surfaces.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid oxidizing conditions to protect the thiol group.
This product integrates thiol-specific reactivity with a hydroxyl handle in a PEG4 chain, specifically offering versatile chemistry for conjugation, surface modification, and multifunctional probe development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
