m-PEG12-acid
This product is a high-purity PEG derivative featuring a terminal carboxylic acid group and a methoxy cap on the opposite end, specifically connected by a PEG12 spacer for solubility and flexibility.
Key Features and Benefits
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Carboxylic Acid Group: Provides a reactive site for amide bond formation with primary amines
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Methoxy Capping: Offers stability and prevents undesired crosslinking
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PEG12 Spacer: Enhances solubility, reduces steric hindrance, and provides longer hydrophilic spacing
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High Purity: Suitable for bioconjugation, surface modification, and drug delivery
Applications
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Amide coupling for protein, peptide, or antibody conjugation
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Functional linker in drug delivery systems
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Surface chemistry for biomaterials and nanoparticles
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Spacer for diagnostic probes and assays
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid moisture and repeated freeze–thaw cycles
This product provides a carboxylic acid group and a methoxy terminus on a PEG12 spacer, enabling especially efficient conjugation with enhanced solubility and reduced steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.