Bocaminooxy PFP acetate

Bocaminooxy PFP acetate

This product is a heterobifunctional reagent featuring a Boc-protected aminooxy group and a tetrafluorophenyl (PFP) ester. The Boc group provides acid-labile protection, while the PFP ester enables efficient amine coupling, making this reagent ideal for stepwise synthesis, bioconjugation, and probe development.

Key Features and Benefits:

• Boc-Protected Aminooxy: Provides orthogonal protection for controlled deprotection.

• PFP Ester: Couples rapidly with amines to form stable amide bonds.

• Dual Reactivity: Supports orthogonal and stepwise conjugation.

• Versatile Design: Enables bioconjugation and synthetic linker strategies.

• High Purity: Ensures reliable results in sensitive applications.

Applications:

• Bioconjugation: Links biomolecules with controlled protection and coupling.

• Drug Delivery: Provides orthogonal handles for PEGylated drug scaffolds.

• Probe Development: Builds multifunctional probes for imaging and diagnostics.

• Synthetic Chemistry: Serves as an intermediate for orthogonal linker design.

Storage and Handling:

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature Boc deprotection.

This product integrates a protected aminooxy group with an amine-reactive ester, specifically offering orthogonal chemistry for advanced synthesis and conjugation strategies.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.